The KANK2 antibody from Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to KANK2. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The KANK2 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, and Western Blot.
Description
Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway(PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus(PubMed:22371500). May be involved in promotion of cell proliferation(By similarity)